Résultats de recherche
Information à la Une Portail ivoirien : l'actualité et l'information en direct sur ivoirematin.com . Infos politiques, internationales, économiques, sportives et culturelles
Imatinib, sold under the brand names Gleevec and Glivec (both marketed worldwide by Novartis) among others, is an oral targeted therapy medication used to treat cancer. Imatinib is a small molecule inhibitor targeting multiple tyrosine kinases such as CSF1R, ABL, c-KIT, FLT3, and PDGFR-β. Specifically, it is used for chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL) that ...
20 juin 2023 · Imatinib is a 2-phenylamino-pyrimidine derivative protein that is a medication used to manage and treat chronic myelogenous leukemia, gastrointestinal stromal tumors, and other malignancies. It is in the tyrosine-kinase inhibitors class of drugs. This activity reviews the indications, action, and contraindications for imatinib as a valuable agent in the treatment of several oncologic indications.
thyroid symptoms - tiredness, dry skin, hair loss, constipation, depression, slow heart rate, weight gain, feeling more sensitive to cold temperatures. Imatinib can affect growth in children and teenagers. Tell your doctor if your child is not growing at a normal rate while using this medicine.
L'imatinib inhibe également les processus cellulaires médiés par le PDGF et le SCF. In vitro, l'imatinib inhibe la prolifération et induit une apoptose des cellules de tumeurs stromales gastro-intestinales (GIST), qui expriment une mutation activatrice du kit. L'activation constitutive du récepteur du PDGF ou des tyrosines kinases Abl ...
19 mai 2014 · Targeted therapy in the form of selective tyrosine kinase inhibitors (TKIs) has transformed the approach to management of various cancers and represents a therapeutic breakthrough. Imatinib was one of the first cancer therapies to show the potential for such targeted action. Imatinib, an oral targeted therapy, inhibits tyrosine kinases ...
chest pain. peeling, blistering, or shedding skin. yellowing of the skin or eyes. blood in the stool. unusual bruising or bleeding. flu-like symptoms, sore throat, fever, chills, and other signs of infection. excessive tiredness or weakness. abdominal pain or bloating. Imatinib may slow growth in children.
Generic Name Imatinib DrugBank Accession Number DB00619 Background. Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. 10 It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with a ...
Imatinib mesylate is approved to treat: Acute lymphoblastic leukemia in adults and children that is Philadelphia chromosome positive. In adults, it is used for cancer that has come back or does not respond to treatment. In children, it is used with chemotherapy as the first treatment after the cancer is diagnosed.
12 déc. 2022 · Call your doctor right away if you have shortness of breath, a big weight gain, a heartbeat that is not normal, or swelling in the arms or legs that is new or worse. If you are 65 or older, use this drug with care. You could have more side effects. This drug may affect growth in children and teens in some cases.
