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  1. 3 avr. 2024 · RAD1 (RAD1 Checkpoint DNA Exonuclease) is a Protein Coding gene. Diseases associated with RAD1 include Mantle Cell Lymphoma. Among its related pathways are Homologous DNA Pairing and Strand Exchange and Homology Directed Repair.

  2. LA FORMATION RAD1. Validé réunion du 5 mai 2022. Composante. C.3 : « Appui au renseignement et à la lutte anti-terroriste » Résultat. R.3 : « Les capacités des services de sécurité sont renforcées pour la prévention et la gestion des risques NRBC-E (nucléaire ; radiologique ; biologique ; engins explosifs) » Activité

  3. We show that the purified Rad1 and Rad10 proteins cut a synthetic bubble structure at the 5′-side of the centrally unpaired region and that Rad1-Rad10 together with purified XPG protein (the human homolog of yeast Rad2 protein) catalyze a dual incision reaction.

    • Adelina A. Davies, Errol C. Friedberg, Alan E. Tomkinson, Richard D. Wood, Stephen C. West
    • 1995
  4. Title: Repair complexes of FEN1 endonuclease, DNA, and Rad9-Hus1-Rad1 are distinguished from their PCNA counterparts by functionally important stability. The RAD1 is loaded to damaged sites where it serves as a platform for the selective recruitment of checkpoint and repair proteins.

  5. 20 avr. 2014 · The manifestation of rad1-K32R's effects at high drug doses suggests that sumoylation influences aspects of Rad1 function that become more critical when the lesion burden is large. To test this idea, we examined how rad1-K32R affects the repair of a single double-strand break via SSA. Rad1-Rad10 cleaves at the ds-ssDNA junction in ...

    • Prabha Sarangi, Zdenka Bartosova, Veronika Altmannova, Cory Holland, Melita Chavdarova, Sang Eun Lee...
    • 2014
  6. 25 oct. 2021 · DNA repair protein (rad1) All proteins in this family for which functions are known are components in a multiprotein endonuclease complex (usually made up of Rad1 and Rad10 homologs). This complex is used primarily for nucleotide excision repair but also for some aspects of recombinational repair in some species.

  7. GeneCards. RAD1. PROTEIN BROWSERi. The Structure section provides predicted structures from the Alphafold protein structure database and includes structures corresponding to uniprot entries mapped to our gene set with at least one splice variant having 100% identity to the structure sequence.

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