Experts in developing products for pharmaceutical, biotechnology, and academic research. dCas9 is fused with transcriptional repressor(s) leading to gene expression repression.
Read Genetics and Genomics research from medical genetics to population genetics. Genetic basis of health and disease, comparative and functional genomics research
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HCMI aims to provide the models’ case-associated data, which includes quality-checked clinical, biospecimen, and molecular characterization data from the models, the tissues from which they were derived, and normal tissues, when available. Available harmonized data are accessible through NCI's Genomic Data Commons.
- Using HCMI
Human Cancer Model Initiative (HCMI) models are available to...
- HCMI Searchable Catalog
HCMI Searchable Catalog is a continuously updated resource...
- Program Background
HCMI was created by a consortium consisting of NCI, Cancer...
- HCMI Publication Guidelines
The Human Cancer Model Initiative (HCMI) is a "community...
- About Next-Gen Models
All of the HCMI next-generation cancer models are derived...
- Cancer Model Development
Genome Characterization Centers (red) are at Broad Institute...
- Genomic Data Commons
Data Scientists & Developers — Join the GDC Analysis Tool...
- Access Data
HCMI: Clinical, biospecimen, and molecular characterization...
- Using HCMI
HCMI Searchable Catalog is a continuously updated resource for querying the available next-generation models developed by HCMI.
Human Cancer Model Initiative (HCMI) models are available to browse at the HCMI Searchable Catalog while models’ case-associated genomic, biospecimen, and molecular data are available at NCI’s Genomic Data Commons.
The Human Cancer Models Initiative (HCMI) is an international consortium that is dedicated to generating novel human tumor-derived culture models with associated genomic and clinical data. The HCMI consortium comprises funding agencies and cancer model development institutions.
1 oct. 2024 · Welcome to the HCMI Searchable Catalog. This message provides privacy and security notices consistent with applicable federal laws, directives, and other federal guidance for accessing this Government system, which includes: this computer network, all computers connected to this network, and. all devices and storage media attached to this ...
4 mars 2021 · The Human Cancer Models Initiative ’s (HCMI’s) Searchable Catalog now has new features that allow users to easily locate models and their case-associated data in the Genomic Data Commons. HCMI is an international collaboration between NCI, Cancer Research UK, Wellcome Sanger Institute, and Hubrecht Organoid Technology.
Il y a 1 jour · Little is known about how the epigenomic states change during development and evolution in a 3D genome context. Here we use Drosophila pseudoobscura with complex turnover of sex chromosomes as a ...
