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Il y a 3 jours · VectorBuilder’s Sequence Alignment tool allows you to not only directly compare two sequences at the DNA or protein level, but also compare two DNA sequences based on translation. You can also design vectors containing your sequence of interest.
Il y a 1 jour · In recent years, machine learning techniques have become a powerful tool for addressing these challenges due to their ability to learn patterns and relationships from large-scale data. Machine learning methods have demonstrated outstanding performance in areas such as protein structure prediction, function annotation, interaction recognition, and physicochemical property prediction. This ...
12 oct. 2024 · VectorBuilder's offers customized mammalian gene expression vectors for delivering your genes of interest into mammalian cells by conventional transfection.
Il y a 3 jours · Up-to-date, commercially available tools predicting protein toxicity based on primary structures were evaluated for their accuracy and usability, using a curated dataset of annotated toxins and non-toxins from UniProt. ToxinPred2 and Toxify emerged as the top performers, showing both high accuracy and suitability for integration into an automated pipeline. Additional bioinformatics methods ...
Il y a 5 jours · Background The bZIP transcription factor family, characterized by a bZIP domain, plays vital roles in plant stress responses and development. While this family has been extensively studied in various plant species, its specific functions in Camelina sativa (False Flax) remain underexplored. Methods and results This study identified 71 bZIP transcription factors in C. sativa, classified into ...
Il y a 2 jours · Salinity stress is one of the most detrimental factors affecting crop production worldwide. Genetic engineering offers a promising approach for improving agronomic traits and enhancing stress tolerance. In a previous work, several potential candidate genes were identified in potato using large-scale functional yeast screening. In this work, we characterized one of the identified genes, an ...
Il y a 3 jours · The IEDB tool forecasted MHC-II and MHC-I binding epitopes of the ROP41 protein for mouse alleles. Through bioinformatics analysis, T-cell epitopes within ROP41 were identified, showcasing a robust potential for binding to MHC-II and MHC-I molecules. Epitopes were cherry-picked for the ROP41 protein based on their minimal percentile ranks, denoting a heightened affinity for the receptor molecule.