Résultats de recherche
Il y a 1 jour · These data indicate that SURF2 depletion promotes both MDM2 and p53 binding to free 5S RNP particles under normal conditions or upon nucleolar stress. To test whether SURF2 depletion modulates ...
Il y a 1 jour · Heat stress during lactation affects the physiological responses, hormonal release, health, and productivity of dairy cows. However, the adverse effects of heat stress on milk synthesis, immune response, and cellular apoptosis in mammary cells remains unknown in Bos indicus cows. This study aimed to understand the relationship between milk yield, milk quality, and the expression of genes ...
Il y a 2 jours · Reliable and ultra-fast DNA and RNA sequencing have been achieved with the emergence of high-throughput sequencing technology. When combining the results of DNA and RNA sequencing for tumor cells of cancer patients, neoantigens that potentially stimulate the immune response of either CD4+ or CD8+ T cells can be identified. However, due to the abundance of somatic mutations and the high ...
Il y a 1 jour · Abstract. Ovarian cancer (OC) represents ecosystems of highly diverse tumor microenvironments (TMEs). The presence of tumor-infiltrating lymphocytes (TILs) is linked to enhanced immune responses and long-term survival. In this review we present emerging evidence suggesting that cellular crosstalk tightly regulates the distribution of TILs ...
Il y a 5 jours · Our findings support the view of metastatic prostate cancer as a systemic disease driven by waves of aggressive clones expanding their niche, infrequently overcoming constraints that otherwise keep them confined in the primary or metastatic site.
Il y a 2 jours · Although largely involuntary, autonomic and neuroendocrine responses are tightly integrated with voluntary behavior executed by the somatic motor system. Running, climbing, and lifting exemplify voluntary actions that have metabolic, cardiovascular, and thermoregulatory consequences.
Il y a 3 jours · Neurological examination revealed an extensive bilateral territory over the upper limbs and neck where there was minimal pain and thermal sensation (see Figure 5–1A). The analgesic region extended from the C5 to the T1 dermatomes (see Figure 4–5).
