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Il y a 3 jours · Journal of Medical Genetics is a leading international peer-reviewed journal covering original research in human genetics, including reviews of and opinion on the latest developments.
Il y a 5 jours · A mutation is any detectable and heritable change in nucleotide sequence that causes a change in genotype and is transmitted to daughter cells and succeeding generations.
Il y a 19 heures · Journal of Human Genetics - Heterozygous mutations in the straitjacket region of the latency-associated peptide domain of TGFB2 cause Camurati–Engelmann disease type II Skip to main content ...
Il y a 5 jours · Paléontologie. Le génome d’un mammouth laineux reconstitué en 3D, à partir de chromosomes « fossiles ». Pour la première fois, des scientifiques ont montré que l’architecture ...
Il y a 5 jours · These mutations suppress the BTZ sensitivity of animals that lack SKN-1A identically to the png-1Δ mutant, confirming that the suppressor mutations do not act by altering SKN-1A activity . We did not test the effect of tald-1 in animals lacking SKN-1A because the skn-1 and tald-1 genes are closely linked, and our attempts to generate a double mutant by crossing were not successful.
Il y a 19 heures · Team explores strategies for correcting mutations that cause stroke. HTRA1 interface mutants exhibit oligomeric assembly defects. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024 ...
Il y a 1 jour · Mutation supply is a key evolutionary hurdle often limiting the adaptation of populations [1,65–67]. As mutation supply depends on population size, one might expect the supply of mutations, for instance to AMR, to be severely limited in small populations, such as the small number of cells forming an infectious propagule of E. coli .
