Yahoo France Recherche Web

Résultats de recherche

1. www.sciencedirect.com › science › articleIntegrated global proteomic and phosphoproteomic analysis of ...

   www.sciencedirect.com › science › article

   Il y a 1 jour · Phosphosite analysis also indicates that four out of the top 10 predicted activated kinases are tyrosine kinases, specifically LTK, ALK, ERBB3, and ERBB4. These kinases are imperative for cell survival, and their activation serves as a cellular countermeasure against cisplatin-induced apoptosis, thereby promoting cell survival.

2. www.nature.com › articles › s41392/024/02009-6Integrate and conquer: pan-cancer proteogenomics uncovers ...

   www.nature.com › articles › s41392/024/02009-6

   Il y a 4 jours · The authors started by analyzing gene mutation, copy-number variations (CNVs), DNA methylation, RNA transcripts, proteomics, phosphosite data, along with an expansive analysis of several drug ...

3. dbpaf.biocuckoo.orgdbPAF - database of Phospho-sites in Animals and Fungi

   dbpaf.biocuckoo.org

   • En cache

   1 oct. 2024 · The dbPAF (d ata b ase of P hospho-sites in A nimals and F ungi) is an online data resource specifically designed for protein phosphorylation in seven eukaryotic species, including H. sapiens, M. musculus, R. norvegicus, D. melanogaster, C. elegans, S. pombe and S. cerevisiae.

4. biosignaling.biomedcentral.com › articles › 10Illuminating the dark kinome: utilizing multiplex peptide ...

   biosignaling.biomedcentral.com › articles › 10

   • En cache

   Il y a 2 jours · Interestingly, the phosphosite containing tyrosine 701 maps to our medium affinity peptide logo (Supplementary Fig. 2E) corroborating the findings in our study . The third approach to assess functional annotation of understudied kinases is with controlled genetic manipulation. The LINCS database hosts over a million transcriptional signatures ...

5. journals.sagepub.com › doi › fullSMC4 serves as a potential marker for the diagnosis and ...

   journals.sagepub.com › doi › full

   Il y a 1 jour · COAD is a relatively common malignancy of the digestive tract and one of the leading types of cancer that cause death worldwide. 1 In 2020, the global incidence rate was 10% and the mortality rate was 9.4%. 2 Due to the lack of effective biomarkers in the early diagnosis and treatment of COAD, patients with COAD are diagnosed in the advanced stage with poor prognosis. 3 Therefore, the further ...

6. gps.biocuckoo.cnGPS 6.0 - Kinase-specific Phosphorylation Site Prediction

   gps.biocuckoo.cn

   • En cache

   1 oct. 2024 · Protein phosphorylation, catalyzed by protein kinases (PKs), is one of the most important post-translational modifications (PTMs), and involved in regulating almost all of biological processes. Here, we report an updated server, Group-based Prediction System (GPS) 6.0, for prediction of PK-specific phosphorylation sites (p-sites) in ...

7. www.nature.com › articles › s41467/024/53178-5Phosphorylation-driven epichaperome assembly is a regulator ...

   www.nature.com › articles › s41467/024/53178-5

   Il y a 3 jours · Recent discoveries have unveiled the existence of specialized chaperone assemblies, known as epichaperomes, which serve as scaffolding platforms that orchestrate the reconfiguration of protein ...