Résultats de recherche
Il y a 1 jour · These data indicate that SURF2 depletion promotes both MDM2 and p53 binding to free 5S RNP particles under normal conditions or upon nucleolar stress. To test whether SURF2 depletion modulates ...
Il y a 1 jour · Heat stress during lactation affects the physiological responses, hormonal release, health, and productivity of dairy cows. However, the adverse effects of heat stress on milk synthesis, immune response, and cellular apoptosis in mammary cells remains unknown in Bos indicus cows. This study aimed to understand the relationship between milk yield, milk quality, and the expression of genes ...
20 sept. 2024 · The differential responses to temperature change in vitro raise questions about the impact of balanced immune responses in vivo through systemic or locally increased temperatures. Unexpectedly, increased temperatures appear to be mutagenic via mitochondrial stress and ROS because heat led p53-deficient cells to accumulate higher numbers of DNA insertions at 39°C when assessed by whole-exome ...
Il y a 1 jour · Abstract. Ovarian cancer (OC) represents ecosystems of highly diverse tumor microenvironments (TMEs). The presence of tumor-infiltrating lymphocytes (TILs) is linked to enhanced immune responses and long-term survival. In this review we present emerging evidence suggesting that cellular crosstalk tightly regulates the distribution of TILs ...
15 sept. 2024 · Practices that improve somatic awareness, like mindful eating, encourage a better understanding of hunger and satiety cues, promoting a healthier digestive system and mitigating issues such as bloating and indigestion.
17 sept. 2024 · What Are 11 Somatic Exercises? Below are 12 unique Somatic Exercises that you can incorporate into your wellness routine: 1. Diaphragmatic Breathing. This exercise helps to activate your body’s relaxation response. It involves deep breathing into the diaphragm rather than shallow breathing from your chest. Steps. Lie down or sit ...
16 sept. 2024 · This study identifies UBAC2 as a phospho-regulated ER-phagy receptor that can suppress the unfolded protein response and sterile inflammation. •. UBAC2 is an ER resident protein that undergoes autophagic degradation upon binding GABARAP. •. UBAC2 promotes ER-phagy flux through its LC3-interacting region (LIR). •.
