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23 juil. 2021 · Two decades after the draft sequence of the human genome was unveiled to great fanfare, a team of 99 scientists has finally deciphered the entire thing. They have filled in vast gaps and...
- What Did The Researchers do?
- What Did They find?
- What Is Next?
Eichler is careful to point out that “this is the completion of a human genome. There is no such thing as thehuman genome.” Any two people will have large portions of their genomes that range from very similar to virtually identical and “smaller portions that are wildly different.” A reference genome can help researchers see where people differ, wh...
For starters, the newly deciphered DNA contains the short arms of chromosomes 13, 14, 15, 21 and 22. These “acrocentric chromosomes” don’t resemble nice, neat X’s the way the rest of the chromosomes do. Instead, they have a set of long arms and one of nubby short arms. The length of the short arms belies their importance. These arms are home to rDN...
One criticism of genetics research is that it has relied too heavily on DNA from people of European descent. CHM13 also has European heritage. But researchers have used the new reference to discover new patterns of genetic diversity. Using DNA data collected from thousands of people of diverse backgrounds who participated in earlier research projec...
3 févr. 2023 · In this Review, we describe how the sequencing of genomes from modern and archaic hominins, great apes and other primates is revealing human-specific genetic changes and how new molecular and...
27 avr. 2023 · By tracing this genomic evolution over the past 100 million years, the so-called Zoonomia Project has revealed millions of stretches of human DNA that have changed little since our...
11 juil. 2024 · The new results come after more than a decade of effort to find fossilized bones and a second genome of a Denisovan, the mysterious archaic human discovered through its DNA 14 years ago. That first Denisovan genome came from a girl’s pinkie finger bone dated between 60,000 to 80,000 years ago.
31 mars 2022 · A research team has finally completed the sequence of the human genome, filling in the last 8 percent of the genome's 3 billion nucleotides. These regions were hard to place on chromosomes...
31 mars 2022 · Extending beyond the human reference genome, large-scale resequencing projects have revealed genomic variation across human populations. Our reanalyses of the 1KGP ( 25 ) and SGDP ( 42 ) datasets have already shown the advantages of T2T-CHM13, even for short-read analyses.
