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Il y a 15 heures · In the 1970s, Brown & Williamson cross-bred a strain of tobacco to produce Y1, a strain containing an unusually high nicotine content, nearly doubling from 3.2 to 3.5%, to 6.5%. In the 1990s, this prompted the Food and Drug Administration to allege that tobacco companies were intentionally manipulating the nicotine content of cigarettes .